Not a technical answer, but still, or even more, important: people who use a scaling of more than 100% most often do this for a reason. One being their bad eyesight.
In the past, accessibility was a feature that needed manual intervention. Since Windows allows scaling, it needs manual intervention to not support accessibility. You don't forget any more to support people with bad eyesight, you actively act against them (some might call this discrimination).
So please, give it a second thought if you really need this approach.