TSQLite3Connection has a Method "SetOpenFlags" which takes as Argument TSQLiteOpenFlags
And those are
TSQLiteOpenFlag = (
sofReadOnly,
sofReadWrite,
sofCreate,
sofNoMutex,
sofFullMutex,
sofSharedCache,
sofPrivateCache,
sofURI,
sofMemory
);
TSQLiteOpenFlags = set of TSQLiteOpenFlag;
btw: Have you activated WAL-Mode?
EDIT: SetOpenFlags is a private Method
You'd actually use the Public Property OpenFlags