You can use the OnShowHint-Event.
<TDrawGrid>.OnShowHint:=@<TDrawGrid>.DoShowHint;
procedure <TDrawGrid>.DoShowHint(Sender: TObject; HintInfo: PHintInfo);
var
ax,ay: byte;
begin
if MouseToCell(HintInfo^.CursorPos.X,HintInfo^.CursorPos.Y,ax,ay) then
HintInfo^.HintStr:='Hello World';
end;